The Story
SAMe is a naturally occurring metabolite found in the human body as well as in plant and animal foods. It is the most active of all methyl donors and has been compared to ATP in its importance for the body. SAMe is naturally synthesized in humans from the amino acid methionine in the presence of the cofactors vitamin B12 and folate. SAMe is involved in the synthesis of neurotransmitters, the hormone melatonin, phospholipids, and polyamines, which control cellular growth. It is also the source of methyl groups inside the nucleus for DNA methylation, which controls gene expression and masking of genetic damage.
Dietary considerations
Gluten free
Dairy free
Soy free
GMO free
Milk free
Casein free
Whey free
Suggested Use: As a dietary supplement, take one capsule per day, preferably on an empty stomach, or as directed by your health care practitioner.
Serving Size: One Capsule
Servings per container: 90
Amount Per Serving
Vitamin B-6 5mg (as Pyridoxal-5-Phosphate)
Folate 170mcg DFE (as Quatrefolic [6S]-5-Methyltetrahydrofolate, glucosamine salt 200mcg)
Vitamin B-12 50mcg (as Methylcobalamin)
SAMe 200mg (as S-Adenosyl-L-Methionine Disulfate P-Toluensulfate)
Other Ingredients: Cellulose (capsule), microcrystalline cellulose, vegetable stearate, calcium chloride anhydrous, calcium oxide.
This product does not contain gluten.
Notice: Color, size or shape may appear different between lots.
Store at room temperature. Keep out of reach of children.
Quatrefolic is covered by U.S. Patent No. 7, 947, 662 and is a registered trademark of Gnosis S.p.A.

Details & Craftsmanship
Every detail has been carefully considered to bring you the perfect product.
Description
SAMe is a naturally occurring metabolite found in the human body as well as in plant and animal foods. It is the most active of all methyl donors and has been compared to ATP in its importance for the body. SAMe is naturally synthesized in humans from the amino acid methionine in the presence of the cofactors vitamin B12 and folate. SAMe is involved in the synthesis of neurotransmitters, the hormone melatonin, phospholipids, and polyamines, which control cellular growth. It is also the source of methyl groups inside the nucleus for DNA methylation, which controls gene expression and masking of genetic damage.
Dietary considerations
Gluten free
Dairy free
Soy free
GMO free
Milk free
Casein free
Whey free
Suggested Use: As a dietary supplement, take one capsule per day, preferably on an empty stomach, or as directed by your health care practitioner.
Serving Size: One Capsule
Servings per container: 90
Amount Per Serving
Vitamin B-6 5mg (as Pyridoxal-5-Phosphate)
Folate 170mcg DFE (as Quatrefolic [6S]-5-Methyltetrahydrofolate, glucosamine salt 200mcg)
Vitamin B-12 50mcg (as Methylcobalamin)
SAMe 200mg (as S-Adenosyl-L-Methionine Disulfate P-Toluensulfate)
Other Ingredients: Cellulose (capsule), microcrystalline cellulose, vegetable stearate, calcium chloride anhydrous, calcium oxide.
This product does not contain gluten.
Notice: Color, size or shape may appear different between lots.
Store at room temperature. Keep out of reach of children.
Quatrefolic is covered by U.S. Patent No. 7, 947, 662 and is a registered trademark of Gnosis S.p.A.












